Publications

Books

A.S. Bommarius and B.R. Riebel, “Biocatalysis – Fundamentals and Applications”, Wiley-VCH, 2004, ISBN: 3-527303-448

 
Other Publications

AS Bommarius, “Amine dehydrogenases occur in nature”, Nature Catalysis News and Views, Nature Catalysis 2019, 2, 288-89 (doi.org/10.1038/s41929-019-0270-2)

 

Refereed Papers
2020

1.       TT Kwok, JR Bright, SR Vora, NJ Chrisandina, MJ Realff, AS Bommarius*, “Solvent selection for Lignin Value Prior to Pulping”, ChemSusChem 2020, 13, 267-273 (doi.org/10.1002/cssc.201901518)

2019
1.     MA McDonald, GD Marshall, AS Bommarius, MA Grover, RW Rousseau*, “Crystallization kinetics of cephalexin monohydrate in the presence of cephalexin precursors”, Crystal Growth & Design 2019, 19, 5065-5074 (doi.org/10.1021/acs.cgd.9b00429)
 
2.     F Tieves, S J-P Willot, MCR Rauch, MMCH van Schie, S Younes, W Zhang, JJ Dong, P Gomez de Santos, JM Robbins, B Bommarius, M Alcalde, AS Bommarius, F Hollmann*, "Formate oxidase from Aspergillus oryzae: one catalyst to promote H2O2-dependent biocatalytic oxidation reactions”, Angew. Chem. Intl. Ed. 2019, 58, 7873-7877 (doi.org/10.1002/anie.201902380)
 
3.     S Tie, B Sreedhar, ME Donaldson, TC Frank, AK Schultz, AS Bommarius, Y Kawajiri*, “Experimental evaluation of simulated moving bed reactor for transesterification reaction synthesis of glycol ether ester", Adsorption 201925, 795-807 (doi.org/10.1007/s10450-019-00048-y)
 
4.     MA McDonald, AS Bommarius, MA Grover, RW Rousseau*, “Direct observation of growth rate dispersion in the reactive crystallization of ampicillin”, Processes 2019, 7, 390 (doi.org/10.3390/pr7060390)
 
5.     TT Kwok, JR Bright, MJ Realff, and AS Bommarius*, “Pretreatment Efficacy and Lignin Solubility of Organic Solvents on Juvenile Slash Pine Chips for Lignin Value Prior to Pulping”, Bioresources 2019, 14(3), 5988-6003 (doi.org/10.15376/biores.14.3.5988-6003)
 
6.     M Dias-Gomes¹, B Bommarius¹, SR Anderson, BD Feske, JM Woodley*, AS Bommarius*, “Bubble Column Enables Higher Reaction Rate for Deracemization of Alcohols with Coupled Alcohol Dehydrogenase/NADH oxidase”, Adv. Synth. Cat., 2019, 361, 2574-2581 (doi.org/10.1002/adsc.201900213)
 
7.     MA McDonald, AS Bommarius*, MA Grover*, RW Rousseau, “Continuous reactive crystallization of β-lactam antibiotics catalyzed by penicillin G acylase. Part II: Case study on ampicillin and product purity", Comp. Chem. Eng. 2019, 126C, 332-341 (doi.org/10.1016/j.compchemeng.2019.04.005)
 
8.     S Tie, B Sreedhar, ME Donaldson, TC Frank, AK Schultz, AS Bommarius, Y. Kawajiri*, “Process Integration for Simulated Moving Bed Reactor for the Production of Glycol Ether Acetate”, Chem. Eng. & Proc.: Process Intensification 2019, 140, 1-10 (doi.org/10.1016/j.cep.2019.04.008)
 
9.     D Franklin, JA Whitley, JM Robbins, AS Bommarius*, “Engineered amine dehydrogenase exhibits altered kinetic mechanism compared to parent with implications for industrial application”, Chemical Engineering J. 2019, 369, 634-640 (doi.org/10.1016/j.cej.2019.03.060)
 
10.     M Gräff, PCF Buchholz, P Stockinger, B Bommarius, AS Bommarius, J Pleiss*, “The Short-chain Dehydrogenase/Reductase Engineering Database (SDRED): a classification and analysis system for a highly diverse enzyme family", Proteins: Structure, Function, and Bioinformatics 2019, 87, 443-451 (DOI: 10.1002/prot.25666).
 
11.     F Tieves, F Tonin, E Fernández-Fueyo, JM Robbins, B Bommarius, AS Bommarius, M Alcalde, F Hollmann*, “Energising the E-factor: the E+-factor”, Tetrahedron 201975, 1311-1314  (doi.org/10.1016/j.tet.2019.01.065)
 
12.     MA McDonald, AS Bommarius, RW Rousseau, and MA Grover*, “Continuous reactive crystal-lization of β-lactam antibiotics catalyzed by penicillin G acylase. Part I: Model development", Comp. Chem. Eng2019123, 331-343 (https://doi.org/10.1016/j.compchemeng.2018.12.029)
 
13.     NJ Chrisandina, TT Kwok, AS Bommarius, MJ Realff*, “Techno-Economic Analysis of Water Precipitation for Lignin Value Prior to Pulping”, Chem. Eng. Res. Des2019143, 4-10 (https://doi.org/10.1016/j.cherd.2018.10.042)

 

2018

1.     *CJ Wilson, AS Bommarius, JA Champion, YO Chernoff, DG Lynn, AK Paravastu, C Liang, M-C Hsieh, JM Heemstra*, “Biomolecular Assemblies: Moving from Observation to Predictive Design”, Chem. Rev. 2018, 118, 11519-11574 (10.1021/acs.chemrev.8b00038)

2.     MD Patil, G Grogan, AS Bommarius, and H Yun*, “Oxidoreductase-catalyzed synthesis of chiral amines”, ACS Catalysis 20188, 10985–11015 (DOI:10.1021/acscatal.8b02924)

3.     JM Robbins, J Geng, BA Barry, G Gadda, AS Bommarius*, "Photo-Irradiation Generates an Ultra-Stable 8-fFAD Semiquinone Radical with Unusual Properties in Formate Oxidase" Biochemistry 2018, 57, 5818-5826 (doi.org/10.1021/acs.biochem.8b00571)

4.     A.A. Caparco, A.S. Bommarius, J.A. Champion*, “Effect of Peptide Linker Length and Composition on Immobilization and Catalysis of Leucine Zipper-Enzyme Fusion Proteins”, AIChE J. 2018, 64, 2934-2946 (doi.org/10.1002/aic.16150)

5.     MD Patil, G Grogan, AS Bommarius, and H Yun*, “Recent advances in transaminase-mediated biocatalysis for the enantioselective synthesis of chiral amines”, Catalysts 20188, 254 (p. 1-25) (http://dx.doi.org/10.3390/catal8070254)

6.      A. Sharma, S.H. Behrens, Y.O. Chernoff, A.S. Bommarius*, “Modulation of the formation of Aβ and Sup35NM amyloids by complex interplay of specific and non-specific ion effects”, J. Phys. Chem. B 2018122, 4972-4981 (DOI: 10.1021/acs.jpcb.7b12836)

7.     H.B. Rose#, T. Greinert#, C. Held*, G. Sadowski, A.S. Bommarius*, “Mutual influence of furfural and furancarboxylic acids on their solubility in aqueous solutions: Experiments and PC-SAFT predictions”, J. Chem. Eng. Data 201863, 1460-1470 (doi: 10.1021/acs.jced.7b01039)

8.     M.A. McDonald, L. Bromig, M.A. Grover, R.W. Rousseau, A.S. Bommarius*, “Kinetic Model Discrimination of Penicillin G Acylase Thermal Deactivation by Non-Isothermal Continuous Activity Assay”, Chem. Eng. Sci., 2018187, 79-86 (doi.org/10/1016/j.ces.2018.04.046)   

9.     MF Paye, HB Rose, JM Robbins, DA Yunda, S Cho, AS Bommarius*, “A high throughput pH-based colorimetric assay: application focus on alpha/beta hydrolases”, Anal. Biochem. 2018, 549, 80-90 (doi.org/10.1016/j.ab.2018.03.009)

10.     JM Oh, B Sreedhar, ME Donaldson, TC Frank, AK Schultz, AS Bommarius, Y Kawajiri*, “Transesterification of propylene glycol methyl ether by reactive simulated moving bed chromatography using homogeneous catalyst”, Adsorption 2018, 24, 309-324 (doi.org/10.1007/s10450-018-9941-6)

11.     J.M. Robbins, G. Gadda*, and A.S. Bommarius*, “Mechanistic Studies of Formate Oxidase from Aspergillus oryzae: A Novel Member of the Glucose-Methanol-Choline Oxidoreductase Enzyme Superfamily that Oxidizes Carbon Acids”, Archives Biochem. Biophys. 2018, 643, 24-31 (doi: 10.1016/j.abb.2018.02.007)

12.     A.F. Miller#*, J.T. Park#, K.F. Ferguson, W. Pitsawong, A.S. Bommarius*, “Informing Efforts to Develop Nitroreductase for Amine Production”, special issue "Flavoproteins”, ed. W. van Berkel;Molecules 201823, 211 (doi: 10.3390/molecules23020211)

 

1986-2017

1.     T.T. Kwok, C.O. Luettgen, M.J. Realff, and A.S. Bommarius*, “Lignin value prior to pulping (LVPP): An advanced pulping concept”, TAPPI J201716(10), 553-5; doi:

2.     J.M. Robbins, M.G. Souffrant, D. Hamelberg, G. Gadda*, A.S. Bommarius*, “Enzyme-Mediated Conversion of Flavin Adenine Dinucleotide (FAD) to 8-Formyl FAD in Formate Oxidase Results in a Modified Cofactor with Enhanced Catalytic Properties”, Biochemistry 201756, 3800-3807; DOI: 10.1021/acs.biochem.7b00335.

3.     L.C.P. Goncalves, S. Milker, D. Kracher, M.J. Fink, F. Rudroff*, R. Ludwig*, A.S. Bommarius,  M.D. Mihovilovic*, "Mutagenesis-independent stabilization of class B flavin monooxygenases in operation",Adv. Synth. Catal. 2017359, 2121-2131 (doi: 10.1002/adsc.201700585)

4.     TT Kwok, DN Fogg, MJ Realff, AS Bommarius*, “Direct Yellow 11: an Alternative Dye for Modified Simons' Staining”, Cellulose 2017, 24, 2367-2373 (DOI 10.1007/s10570-017-1269-y)

5.     MA McDonald, AS Bommarius*, RW Rousseau, “Enzymatic reactive crystallization for improving ampicillin synthesis”, Chem. Eng. Sci2017165, 81-88; DOI 10.1016/j.ces.2017.02.040 

6.     MJ Mistilis, JC Joyce, ES Esser, I Skountzou, RW Compans, AS Bommarius, MR Prausnitz*, “Long-term stability of influenza vaccine in a dissolving microneedle patch”, Drug Deliv. and Transl. Res.20177, 195-205; DOI 10.1007/s13346-016-0282-2

7.     J.M. Oh, B. Sreedhar, M.E. Donaldson, T.C. Frank, A.K. Schultz, A.S. Bommarius, Y. Kawajiri, “Transesterification of propylene glycol methyl ether in chromatographic reactors using anion exchange resin as a catalyst”, J. Chromatography A 2016, 1466, 84-95; (DOI:10.1016/j.chroma.2016.08.072)

8.     S. Tie, B. Sreedhar, G. Agrawal, J. Oh, M. Donaldson, T. Frank, A.S. Bommarius, Y. Kawajiri, “Model-Based Determination of Optimal Operation and Experimental Validation of Simulated Moving Bed Reactor for Production of Glycol Ether Ester”, Chem. Eng. J. 2016, 301, 188-199; doi: http://dx.doi.org/10.1016/j.cej.2016.04.062

9.     L.G. Encarnación-Gómez, A.S. Bommarius, R.W. Rousseau, “Reactive crystallization of β-lactam antibiotics: Strategies to enhance productivity and purity of ampicillin”, Reaction Chemistry and Engineering 2016, 1, 321-9; DOI: 10.1039/C5RE00092K

10.  L.G. Encarnación-Gómez, A.S. Bommarius, R.W. Rousseau, “Crystallization kinetics of ampicillin using online monitoring tools and robust parameter estimation”, Ind. Eng. Chem. Res. 2016, 55, 2153–2162; DOI: 10.1021/acs.iecr.5b03880

11.  A. Sharma, K.L. Bruce, B. Chen, S. Jyoneva, S.H. Behrens, A.S. Bommarius*, Y.O. Chernoff*, “Contributions of the Prion Protein Sequence, Strain and Environment to the Species Barrier”, J. Biol. Chem. 2016, 291, 1277–1288; DOI 10.1074/jbc.M115.684100

12.  M.J. Mistilis, J.C. Joyce, E.S. Esser, I. Skountzou, R.W. Compans, A.S. Bommarius, M.R. Prausnitz, “Long-term stability of influenza vaccine in a dissolving microneedle patch”, Drug Delivery and Translational Research 2016, 000 (in press); DOI 10.1007/s13346-016-0282-2

13.  R.M. Clairmont, A.S. Bommarius, and A.L. Weber, “Synthesis of iNHC from a two-reaction network: an indirect approach to small molecule duplication”, J. Mol. Evol. 201581, 1-9 (DOI 10.1007/s00239-015-9687-7)

14.  K.S. Sarkisyan, A.S. Goryashchenko, P.V. Lidsky, D.A. Gorbachev, N.G. Bozhanova, A.Yu. Gorokhovatsky, A.R. Pereverzeva, A.P. Ryumina, V.V. Zherdeva, A.P. Savitsky, K.M. Solntsev, A.S. Bommarius, G.V. Sharonov, J.R. Lindquist, M. Drobizhev, T. Hughes, A. Rebane, K. Lukyanov, A. Mishin, "Green fluorescent protein with anionic tryptophan-based chromophore and long fluorescence lifetime", Biophysical Journal 2015109, 380-389    (http://dx.doi.org/10.1016/j.bpj.2015.06.018)

15.  C.L. Walker, K.A. Lukyanov, I.V. Yampolsky, A.S. Mishin, A.S. Bommarius, A.M. Duraj-Thatte, B. Azizi, L.M. Tolbert, K.M. Solntsev, “Fluorescence imaging using synthetic GFP chromophores”, Curr. Opin. Chem. Biol. 201527, 64–74

16.  A.S. Bommarius, “Biocatalysis, a status report”, Annual Review of Chemical and Biomolecular Engineering 20156, 319-345 (doi: 10.1146/annurev-chembioeng- 061114-123415)

17.  R.B. Vegh, D.A. Bloch, A.S. Bommarius, M. Verkhovsky, S. Pletnev, H. Iwaï, A.V. Bochen-kova,* and K.M. Solntsev*, “Hidden Photoinduced Reactivity of the Blue Fluorescent Protein mKalama1”, Chem. Phys. Phys. Chem. 201517, 12472 - 12485 (DOI: 10.1039/c5cp00887e)

18.  J.T. Park, L.M. Gómez Ramos, A.S. Bommarius, “Engineering towards Nitroreductase Functionality in Ene-reductase Scaffolds”, ChemBioChem 201516, 811-818 (doi: 10.1002/cbic.201402667)

19.  M.J. Mistilis, A.S. Bommarius, M.P. Prausnitz, “Development of a thermostable microneedle patch for influenza vaccination”, J. Pharm. Sci., special issue commemorating Russ Middaugh, 2015104, 740-749 (DOI 10.1002/jps.24283)

20.  L.G. Encarnación-Gómez, A.S. Bommarius, and R.W. Rousseau, “Reactive crystallization of enantiomers: Chemoenzymatic stereoinversion of chiral amino acids in saturated conditions”, Chem. Eng. Sci. 2015122, 416-425 (DOI: 10.1016/j.ces.2014.09.055)

21.  J. Oh, G. Agrawal, B. Sreedhar, M.E. Donaldson, A.K. Schultz, T.C. Frank, A.S. Bommarius, Y. Kawajiri, “Conversion Improvement for Catalytic Synthesis of Propylene Glycol Methyl Ether Acetate by Reactive Chromatography: Experiments and Parameter Estimation”, Chem. Eng. J. 2015259, 397-409

22.  Y. Kang, M. Sohn, J.L. Lee, M.J. Realff, A.S. Bommarius, „An effective chemical pretreatment method for lignocellulosic biomass with substituted imidazoles“, Biotechnol. Progr. 201531, 25-34 (DOI: 10.1002/btpr.2005)

23.  L.G. Encarnación-Gómez, A.S. Bommarius, and R.W. Rousseau, “Reactive crystallization of enantiomers: Chemoenzymatic stereoinversion of chiral amino acids in saturated conditions”, Chem. Eng. Sci. 2015122, 416-425 (DOI: 10.1016/j.ces.2014.09.055)

24.  J. Oh, G. Agrawal, B. Sreedhar, M. E. Donaldson, A. K. Schultz, T. C. Frank, A. S. Bommarius, Y. Kawajiri, “Conversion Improvement for Catalytic Synthesis of Propylene Glycol Methyl Ether Acetate by Reactive Chromatography: Experiments and Parameter Estimation”, Chem. Eng. J. 2015259, 397-409

25.  B.R. Bommarius, M. Schürmann, A.S. Bommarius, “A chimeric amine dehydrogenase offers surprising properties not found in either parent”, Chem. Commun. 201450(95), 14953-55 (DOI: 10.1039/C4CC06527A)

26.  S.K. Au, B. Bommarius, A.S. Bommarius, “Biphasic reaction system allows for conversion of hydrophobic substrates by amine dehydrogenases ”, ACS Catalysis 20144, 4021-4026 (DOI 10.1021/cs4012167)

27.  G. Agrawal, J. Oh, B. Sreedhar, S. Tie, M.E. Donaldson, T.C. Frank, A.K. Schultz, A.S. Bommarius, Y. Kawajiri, “Reactive simulated moving bed systems with modulation of feed concentration for production of glycol ether ester”, J. Chromatography A 20141360, 196-208

28.  A.S. Bommarius, M. Sohn, Y. Kang, J.H. Lee, M.J. Realff, "Protein engineering of cellulases", Current Opinion in Biotechnology, special issue "Cell and Pathway Engineering", eds.: Tina Lütke-Eversloh & Keith E. J. Tyo; 201429, 139-145

29.  R.B. Vegh, K.B. Bravaya , D.A. Bloch, A.S. Bommarius, L.M. Tolbert, M. Verkhovsky, A. I. Krylov, K.M. Solntsev, “Chromophore photoreduction in red fluorescent proteins is responsible for bleaching and phototoxicity”, J. Phys. Chem. B 2014118, 4527–34

30.  A.L. Deaguero and A.S. Bommarius, “In Situ Mixed Donor Synthesis of Ampicillin with Ethylene Glycol Co-Solvent”, Biotechnol. Bioeng. 2014111, 1054-1058

31.  J. Rubin, A. Sharma, L. Linden, A.S. Bommarius, S.H. Behrens, “Gauging Colloidal and Thermal Stability in human IgG1 – Sugar Solutions through Diffusivity Measurements”, J. Phys. Chem. B 2014118, 2803-2809

32.  J. Rubin, L. Linden, W.M. Coco, A.S. Bommarius, S.H. Behrens, “Salt-Induced Aggregation of a Monoclonal Human Immunoglobulin G1”, J. Pharm. Sci. 2013102, 377-386

33.  M.J. Abrahamson, J.W. Wong, A.S. Bommarius, “The rapid evolution of an amine dehydrogenase biocatalyst for the asymmetric production of chiral amines“ , Adv. Synth. Catal.2013,355, 1780-1786

34.  A.S. Bommarius and M.F. Paye, “Stabilizing biocatalysts”, Chemical Society Reviews 2013, 42 (15), 6534-6565 (Special Issue: Enzyme Immobilization), eds.: Ulf Hanefeld, Linqiu Cao

35.  Y. Kang, P. Bansal, M.J. Realff, A.S. Bommarius, “SO2-Catalyzed Steam Explosion: The Effects of Different Severity on Digestibility, Accessibility and Crystallinity of Lignocellulosic Biomass”, Biotechnol. Progress 201329, 909-916

36.  J.K. Blum, W.D. Ricketts, and A.S. Bommarius, “Improved thermostability of amino ester hydrolase (AEH) by combining B-FIT analysis and structure-guided consensus method”, J. Biotechnol. 2012160, 214-221

37.  M.J. Abrahamson, E. Vazquez-Figueroa, N.B. Woodall, J.C. Moore, A.S. Bommarius, “Development of a Novel Amine Dehydrogenase for Synthesis of Chiral Amines“, Angew. Chem. Intl. Ed. 201251, 3969-3972

38.  A.L. Deaguero, J.K. Blum, and A.S. Bommarius, “Improving the Diastereoselectivity of Penicil-lin G Acylase for Ampicillin Synthesis from Racemic Substrates”, Prot. Eng. Des. Select. 201225, 135-144

39.  P. Bansal, B.J. Vowell, M. Hall, M.J. Realff, J.H. Lee, A.S. Bommarius, “Elucidation of Cellulose Accessibility, Hydrolysability and Reactivity as the Major Limitations in the Enzymatic Hydrolysis of Cellulose”, Biores. Technol2012107, 243-250

40.  H.S. Castillo, A.M. Ousley, A. Duraj-Thatte, K.N. Lindstrom, D.D. Patel, A.S. Bommarius, B. Azizi, “The Role of Residue C410 on Activation of the Human Vitamin D Receptor by Various Ligands”, J. Steroid Biochem. Mol. Biol2012128, 76-86

41.  H. Shaffer, E. Chang, A. Bommarius, D. Doyle, B. Azizi, “BAPJ69-4A: A Yeast Two-Hybrid Strain for Both Positive and Negative Genetic Selection”, FEBS J., in press

42.  M. Hall, J. Rubin, S.H. Behrens, and A.S. Bommarius, “The Cellulose-Binding Domain of Cellobiohydrolase Cel7A from Trichoderma reesei Is Also a Thermostabilizing Domain”, J. Biotechnol. 2011155, 370-376

43.  M. Hall and A. S. Bommarius, "Enantioenriched compounds via enzyme-catalyzed redox reactions”, Chem. Rev. 2011111, 4088-4110

44.  J.T. Park, J.I. Hirano, V. Thangavel, B.R. Riebel, A.S. Bommarius, “NAD(P)H oxidase V from Lactobacillus plantarum V (NoxV) displays enhanced operational stability even in absence of reducing agents”, J. Mol. Catal. B Enz201171, 159-165

45.  Y. Yanto, C. K. Winkler, S.J. Lohr, M. Hall, K. Faber, and A.S. Bommarius, “Asymmetric Bioreduction of Alkenes Using Ene Reductases YersER and KYE1, and Effects of Organic Solvents”, Org. Lett., 2011, 13, 2540-43

46.  R.B. Vegh, K.M. Solntsev, M.K. Kuimova, S.H. Cho, Y.A. Liang, B.L.W. Loo, L.M. Tolbert, and A.S. Bommarius, “Reactive Oxygen Species in the Photochemistry of the Fluorescent Protein “Killer Red” “, Chem. Comm. 201147, 4887-4889

47.  A.S. Bommarius, J.K. Blum, and M.J. Abrahamson, “Status of Protein Engineering for Bio-catalysts: How to design an industrially useful biocatalyst”, Curr. Opin. Chem. Biol. 2011, 15, 194-200 

48.  M. Hall, P. Bansal, J.H. Lee, M.J. Realff, A.S. Bommarius, “Biological pretreatment of cellulose: Enhancing enzymatic hydrolysis rate using cellulose-binding domains from cellulases”, Biores. Technol. 2011102, 2910-15

49.  ERRATUM: “Correlating aggregation kinetics and stationary diffusion in protein- sodium salt systems observed with dynamic light scattering”, J. Rubin, A. San Miguel, A.S. Bommarius, S.H. Behrens, J. Phys. Chem. B 2011115, 10778-78

50.  M.R. Prausnitz and A.S. Bommarius, “Drug Design, Development, and Delivery: An Interdisciplinary Course on Pharmaceuticals”, J. Chem. Eng. Educ201145, 47-52

51.  J.K. Blum and A.S. Bommarius, “Amino Ester Hydrolase from Xanthomonas campestris pv. campestris, ATCC 33913 for Enzymatic Synthesis of Ampicillin”, J. Mol. Catal. B: Enzymatic 201067, 21-28

52.  J.K. Blum, A.L. Deaguero, C.V. Perez, and A.S. Bommarius, „"Ampicillin synthesis using a two-enzyme cascade with both alpha-Amino Ester Hydrolase and Penicillin G Acylase"ChemCatChem 20102, 987-991

53.  M. Hall, Y. Yanto, and A.S. Bommarius, ‘Old Yellow Enzyme’ family and Enoate Reductases: Asymmetric Reduction of C=C Bonds and Activity on Nitro Compounds, The Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology (ed; M. Flickinger), Wiley, 2010, 2234-2247

54.  A.L. Deaguero, J.K. Blum, A.S. Bommarius, Biocatalytic synthesis of beta-lactam antibiotics, The Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology (ed; M. Flickinger), Wiley, 2010, 535-567

55.  Y. Yanto, M. Hall, and A.S. Bommarius, Nitroreductase from Salmonella typhimurium: characterization and catalytic activity, Org. Biomol. Chem. 20108, 1826-1832

56.  J. Rubin, A. San Miguel, A.S. Bommarius, S.H. Behrens, Correlation of aggregation kinetics and stationary diffusion in protein - sodium salt systems observed with dynamic light scattering, J. Phys. Chem. B 2010114, 4383-4387

57.  P. Bansal, M. Hall, M.J. Realff, J.H. Lee, and A.S. Bommarius, Multivariate statistical analysis of X-ray data from cellulose: A new method to determine degree of crystallinity and predict hydrolysis rates, Bioresource Technol. 2010101, 4461-4471

58.  V. Yeh, J.M. Broering, B. Chen, A. Romanyuk, Y.O. Chernoff, A.S. Bommarius, The Hofmeister effect on Amyloid Formation Using Yeast Prion Protein, Protein Science 201019, 47-56

59.  T.A. Rogers and A.S. Bommarius, Utilizing Simple Biochemical Measurements to Predict Lifetime Output of Biocatalysts in Continuous Isothermal Processes, Chem. Eng. Sci. 201065, 2118-2124

60.  M. Hall, P. Bansal, J.H. Lee, M.J. Realff, and A.S. Bommarius, Cellulose Crystallinity: a Key Predictor of Enzymatic Hydrolysis Rate, FEBS J2010277, 1571-1582

61.  P. Bansal, M. Hall, M. J. Realff, J. H. Lee, A. S. Bommarius. Modeling Cellulase Kinetics on Lignocellulosic Substrates. Biotechnol. Adv. 200927, 833-848.

62.  T. A. Rogers, R. M. Daniel, A. S. Bommarius, “Deactivation of TEM-1 b -lactamase investigated by isothermal batch and non-isothermal continuous enzyme membrane reactor methods”, ChemCatChem 20091, 131-137.

63.  B.L.W. Loo, A. Dubey, M.J. Realff, J.H. Lee, and A.S. Bommarius, “Analysis of recombinant sequences for interacting residues can improve the quality of combinatorial library: case study on fluorescent proteins”, Biotech. J. 20083, 63-73

64.  A.S. Bommarius, Adrian Katona, Sean E. Cheben, Arpit S. Patel, Arthur J. Ragauskas, Kristina Knudson, and Yunqiao Pu, “Cellulase kinetics as a function of cellulose pretreatment”, Metab. Eng. 200810, 370-381

65.  J.M. Broering and A.S. Bommarius, “A kinetic model for salt-induced protein deactivation”, J. Phys. Chem. B. 2008112, 12768–12775

66.  N. Kothari, A.A. Jafarpour, R.P. Trebino, T.L. Thaler, A.S. Bommarius, “Astrobiological polarimeter”, Astrobiology 2008, 8, 1061-1069.

67.  E. Vázquez-Figueroa, V. Yeh, J.M. Broering, J.F. Chaparro-Riggers, and A.S. Bommarius, “Thermostable Variants Constructed via the Structure-guided Consensus Method also Show Increased Stability in Salt Solutions and Homogeneous Aqueous-Organic Media”, Protein Eng. Des. Sel. 200821, 673-680

68.  J.F. Chaparro-Riggers, K.M. Polizzi, E. Vazquez-Figueroa, T.A. Rogers, and A.S. Bommarius, “Comparison of three Enoate Reductases and their potential use for biotransformations”, Adv. Synth. Catal. 2007349, 1521-1531

69.  J.M. Broering and A.S. Bommarius, “Cation and strong cosolute effects on protein kinetic stability”, Biochem. Soc. Trans200735, 1602-5.

70.  E. Vazquez-Figueroa, J.F. Chaparro-Riggers, and A.S. Bommarius, “Development of a Thermostable Glucose Dehydrogenase via a Structure-guided Consensus Concept”, ChemBioChem 20078, 2295-2301.

71.  J.F. Chaparro-Riggers, B.L.W. Loo, K.M. Polizzi, P.R. Gibbs, X.-S. Tang, M.J. Nelson, and A.S. Bommarius, „Revealing Biases Inherent in Recombination Protocols“, BMC Biotechnology 20077, 77

72.  E.M. Hill, J.M. Broering, J.P. Hallett, C.L. Liotta, C.A. Eckert, and A.S. Bommarius, “Coupling Chiral Homogeneous Biocatalysis with Benign Heterogeneous Separation”, Green Chemistry 20079, 888-893

73.  K.M. Polizzi, D.A. Moore, and A.S. Bommarius, “A short-chain dehydrogenase/reductase from Vibrio vulnificus with both blue fluorescence and oxidoreductase activity”, Chem. Comm. 2007, 1843-5

74.  K.M. Polizzi, A.S. Bommarius, J.M. Broering, J.F. Chaparro-Riggers, “Stability of enzymes”, Curr. Opin. Chem. Biol. 200711, 220-225

75.  J.F. Chaparro-Riggers, K.M. Polizzi, A.S. Bommarius, “Better library design: data-driven protein engineering”, Biotechnol. J. 20072, 180-191

76.  T.L. Thaler, P.R. Gibbs, R.P. Trebino, and A.S. Bommarius, “Search for Extraterrestrial Life Using Chiral Molecules: Mandelate Racemase as a Test Case”, Astrobiology 20066, 910-920

77.  A.S. Bommarius, J.M. Broering, J.F. Chaparro-Riggers and K.M. Polizzi, “High-Throughput Screening for enhanced stability of proteins” , Curr. Opin. Biotechnology 200618, 606-610

78.  A. Dubey, M.J. Realff, J.H. Lee, and A.S. Bommarius, “Identifying the Interacting Positions of a Protein using Boolean learning and Support Vector Machines”, Comp. Biol. Chem. 200630, 268-279

79.  G.T. Lountos, R. Jiang, W.B. Wellborn, T.L. Thaler, A.S. Bommarius and A.M. Orville, “The Crystal Structure of NAD(P)H Oxidase from Lactobacillus sanfranciscensis: Insights into the Conversion of O2 into Two Water Molecules by the Flavoenzyme“, Biochemistry 200645, 9648-9659

80.  K.M. Polizzi, M. Parikh, C.U. Spencer, I. Matsumura, J.H. Lee, M.J. Realff, and A.S. Bommarius, “Pooling for Improved Screening of Combinatorial Libraries for Directed Evolution” , Biotechnol. Progr. 200622, 961-967

81.  J.M. Broering, E.M. Hill, J.P. Hallett, C.L. Liotta, C.A. Eckert, and A.S. Bommarius, "Biocatalytic reaction and recycle using CO2-induced Organic Aqueous Tunable Solvents (OATS)", Angew. Chem. Intl. Ed. 200645, 4670-4673

82.  K.M. Polizzi&, J.F. Chaparro-Riggers&, E. Vazquez-Figueroa, and A.S. Bommarius, “Structure-guided consensus approach to create a more thermostable penicillin G acylase”, Biotechnology J. 20061, 531-536

83.  A.S. Bommarius and K.M. Polizzi, “Novel biocatalysts: recent developments”, Chem. Eng. Sci. 2006, 61, 1004-1016

84.  K.M. Polizzi, C.U. Spencer, A. Dubey, I. Matsumura, J.H. Lee, M.J. Realff, and A.S. Bommarius, “Simulation modeling of pooling for combinatorial protein engineering”, J. Biomol. Screening, 200510, 856-864

85.  A.S. Bommarius and A. Karau, “Deactivation of formate dehydrogenase (FDH) in solution and at gas-liquid interfaces”, Biotechnol. Progr. 200521, 1663-1672

86.  J.M. Broering and A.S. Bommarius, „Evaluation of Hofmeister effects on the kinetic stability of proteins“, J. Phys. Chem. B 2005109, 20612-19

87.  A.S. Bommarius and J.M. Broering, ““Established and novel tools to investigate biocatalyst stability”, Biocatalysis and Biotransformation 200523, 125-139

88.  R. Jiang, B.R. Riebel and A.S. Bommarius, “Comparison of competing oxygen reduction pathways in Lactococcus lactis: four-electron vs. two-electron reduction by NADH oxidases”, Adv. Synth. Cat. 2005347, 1139-1146

89.  P.R. Gibbs, C.S. Uehara, U. Neunert, and A.S. Bommarius, “Accelerated biocatalyst stability testing for process optimization”, Biotech. Progr. 200521, 762-774

90.  A. Dubey, M.J. Realff, J.H. Lee, and A.S. Bommarius, “Support Vector Machines for Predicting the Critical Positions of a Protein”, J. Theor. Biol. 2005234, 351-361

91.  G.T. Lountos, B.R. Riebel, W.B. Wellborn, A.S. Bommarius, A.M. Orville, "Crystallization and Preliminary Analysis of a Water-Forming NADH Oxidase from Lactobacillus sanfranciscensis", Acta Cryst. D, 200460, 2044-47

92.  R. Jiang and A.S. Bommarius, "Hydrogen peroxide-producing NADH oxidase (nox 1) from Lactococcus lactis", Tetrah. Asymm. 200415, 2939-44

93.  P. Ödman, W.B. Wellborn, A.S. Bommarius, "An enzymatic process to -ketoglutarate from L-glutamate: the coupled system L-glutamate dehydrogenase/NADH oxidase", Tetrah. Asymm. 200415, 2933-37

94.  J. Lu, M.J. Lazzaroni, J.P. Hallett, A.S. Bommarius, C.L. Liotta, and C.A. Eckert, "Tunable Solutions for Homogeneous Catalyst Recycle", I&EC Research 200443, 1586-1590

95.  B.R. Riebel, P.R. Gibbs, W.B. Wellborn, and A.S. Bommarius, "Cofactor regeneration of both NAD+ from NADH and NADP+ from NADPH: NADH oxidase from Lactobacillus sanfranciscensis", Adv. Synth. Cat.2003345, 707-712

96.  B.R. Riebel, P.R. Gibbs, W.B. Wellborn, and A.S. Bommarius, "Cofactor regeneration of NAD+ from NADH: novel water-forming NADH oxidases", Adv. Synth. Cat.2002344, 1156-1169

97.  O. May, S. Verseck, A.S. Bommarius, and K. Drauz, "Development of Dynamic Kinetic Resolution Processes for Biocatalytic Production of Natural and Nonnatural L-Amino Acids", Organic Process Research & Development. 20026, 452-457

98.  J. Wöltinger, K. Drauz and A. S. Bommarius, "The Membrane Reactor in the Fine Chemicals Industry", Appl. Catalysis A: General. 2001221, 171–185

99.  S. Verseck, A.S. Bommarius and M.-R. Kula, "Screening, Overexpression and Characterization of an N-Acylamino Acid Racemase from Amycolatopsis orientalis subsp. lurida", Appl. Microbiol. Biotechnol. 200155, 354-361

100.     A.S. Bommarius, M. Schwarm and K. Drauz, "Comparison of Different Chemoenzymatic Process Routes to Enantiomerically Pure Amino Acids", Chimia 200155, 50-59

101.     J. Wöltinger, H. Henniges, A.S. Bommarius, H.-P. Krimmer and K. Drauz, "Application of the continuous Sharpless-dihydroxylation", Tetrahedron Asymmetry 200112, 2095-2098

102.     J. Wöltinger, A.S. Bommarius, K. Drauz and C. Wandrey, "The Chemzyme Membrane Reactor in the Fine Chemicals Industry", Organic Process Research & Development, 2001, 5, 241-248

103.     A.S. Bommarius, K. Drauz, S. Eils, J. Kirchhoff and M. Schwarm, "Reduction Technologies in the Industrial Synthesis of Fine Chemicals", Chimica Oggi 2000, 18, 12-17

104.     A.S. Bommarius, M. Schwarm and K. Drauz, "Biocatalysis to Amino Acid-based Chiral Pharmaceuticals - Examples and Perspectives", J. Mol. Cat B: Enzymatic 19985, 1-11

105.     U. Eichhorn, A.S. Bommarius, K. Drauz and H.-D. Jakubke, "Synthesis of dipeptides by suspension-to-suspension conversion via thermolysin catalysis - from analytical to preparative scale", J. Peptide Science 19973, 245-251

106.     G. Krix, A.S. Bommarius, K. Drauz, M. Kottenhahn, M. Schwarm and M.-R. Kula, "Enzymatic reduction of a-keto acids leading to L-amino acids or D-hydroxy Acids", J. Biotechnology 199753, 29-39;

107.     A.S. Bommarius, K. Drauz, K. Günther, G. Knaup and M. Schwarm, "L-Methionine Related L-Amino Acids by Acylase Cleavage of Their Corresponding N-Acetyl-DL-Derivatives", Tetrahedron Asymmetry 19978, 3197-3200

108.     U. Stelkes-Ritter, G. Beckers, A.S. Bommarius, K. Drauz, K. Günther, M. Kottenhahn, M. Schwarm and M.-R. Kula, "Kinetics of peptide amidase and its application for the resolution of racemates", Biocatalysis and Biotransformations 199715, 205-219

109.     A.S. Bommarius, M. Schwarm and K. Drauz, "The membrane reactor for the acylase process - from laboratory results to commercial scale", Chimica Oggi 1996, 14(10), 61-64;

110.     A.S. Bommarius, D.I.C. Wang and T.A. Hatton, "Xanthine Oxidase Reactivity in Reversed Micellar Systems: A Contribution to the Prediction of Enzymatic Activity in Organized Media", J. Amer. Chem. Soc. 1995, 117, 4515-4523;

111.     U. Joeres, A.S. Bommarius, J. Thömmes & M.-R. Kula, "Studies on the kinetics and application of L-carnitine amidase for production of L-carnitine", Biocatalysis & Biotransformation 1995, 12, 27-36;

112.     U. Eichhorn, A.S. Bommarius, K. Drauz and H.-D. Jakubke, "Environmentally acceptable synthesis of peptides in high yields by suspension-to-suspension conversion via protease catalysis", PEPTIDES 1994, (Hrsg.: H.L.S. Maia), Escom, Leiden, 1995, 226-7;

113.     T.A. Hatton and A.S. Bommarius, "A population balance analysis of substrate distribution effects on enzymatic reaction rates in reversed micelles", Proceedings of the Material Research Society 1995, 366, 439-444;

114.     A.S. Bommarius, M. Schwarm, K. Stingl, M. Kottenhahn, K. Huthmacher and K. Drauz, "Synthesis and Use of Enantiomerically Pure tert.-Leucine", Tetrahedron Asymmetry 1995, 6, 2851-2888;

115.     A. Fischer, A.S. Bommarius, K. Drauz and C. Wandrey, "A novel approach to enzymatic peptide synthesis using highly solubilizing Na-protecting groups of amino acids", Biocatalysis 1994, 8, 289-307;

116.     A.S. Bommarius, K. Drauz, W. Hummel, M.-R. Kula and C. Wandrey, "Some new developments in reductive amination with cofactor regeneration", Biocatalysis 1994, 10, 37-47;

117.     A.S. Bommarius and K. Drauz, "An Enzymatic Route to L-Ornithine from Arginine - Activation, Selectivity and Stabilization of L-Arginase", Bioorganic and Medicinal Chemistry 1994, 2, 617-626;

118.     C. Petit, A.S. Bommarius, M.-P. Pileni and T.A. Hatton, "Characterization of a Four-Component Cationic Reversed Micellar System: DTAC/Hexanol/n-Heptane/0.1 M KCl Solution", J. Phys.Chem. 1992, 96, 4653-58;

119.     A.S. Bommarius, K. Drauz, H. Klenk und C. Wandrey, "Operational Stability of Enzymes - Acylase-Catalyzed Resolution of N-Acetyl Amino Acids to Enantiomerically Pure L-Amino Acids", Annals N.Y. Acad. Sci. (Enzyme Eng. XI) 1992, 672, 126-36;

120.     A.S. Bommarius, M. Kottenhahn, H. Klenk and K. Drauz, "A versatile direct route from hydantoins to D-amino acids employing a resting cell biocatalyst with D-hydantoinase and D-carbamoylase activity", in: "Microbial Reagents in Organic Synthesis", ed.: S. Servi, Kluwer Acad. Publ., Dordrecht, London, Boston, NATO ASI Series 1992, C 381, 161-174;

121.     E.B. Leodidis, A.S. Bommarius and T.A. Hatton, "Amino Acids in Reversed Micelles: Dependence of the Interfacial Partition Coefficient on Excess Phase Salinity and Interfacial Curvature", J. Phys. Chem. 1991, 95, 5943-56;

122.     A.S. Bommarius, K. Makryaleas & K. Drauz, "An Enzymatic Route to L-Ornithine from L-Arginine; Activation and Stabilization Studies on L-Arginase", Biomed. Biochim. Acta 1991, 50, 249-55

123.     A. Fischer, A. Schwarz, C. Wandrey, A.S. Bommarius, G. Knaup and K. Drauz, "Preparative-scale enzyme-catalyzed peptide synthesis using solubilizing N-terminal protecting groups", Biomed. Biochim. Acta 1991, 50, 169-74

124.     A.S. Bommarius, J.F. Holzwarth, D.I.C. Wang & T.A. Hatton, "Coalescence and Solubilizate Exchange in a Cationic Four Component Reversed Micellar System", J. Phys. Chem. 1990, 94, 7232-39

125.     A.S. Bommarius, J.F. Holzwarth, D.I.C. Wang and T.A. Hatton, "A Population Balance Model for the Determination of Solubilizate Exchange Rate Constants in Reversed Micellar Systems", in: "Structure, Dynamics, and Equilibrium Properties in Colloidal Systems", NATO ASI Series C 1990, 324, 181-99, eds.: H.B. Bloor & E. Wyn-Jones, Kluwer Acad. Publ., Dordrecht, London, Boston

126.     J.W. Shield, H.D. Ferguson, A.S. Bommarius and T.A. Hatton, "Enzymes in Reversed Micelles as Catalysts for Organic-Phase Reactions"; Ind. Eng. Chem. Fundam. 1986, 25, 603-612